Rare Solitary Neurofibroma of the Palate in a Pediatric Patient: A Case Report
DOI:
https://doi.org/10.22452/adum.vol32.4Keywords:
Neurofibroma, palate, solitary, Paediatric, Neurofibromatosis type1Abstract
Neurofibroma is a benign nerve tumour originating from the peripheral nerve sheath, a variable mixture of Schwann cells, perineural-like cells, and fibroblasts. it may arise either as a solitary tumour or be a component of neurofibroma and von Recklinghausen’s disease. In rare cases, multiple neurofibromas may develop without any associated syndrome. The solitary type seldom affects the head and neck areas, particularly the oral cavity. Although some cases have been documented on the buccal mucosa, floor of the mouth, lips, and gingiva, neurofibromas on the hard palate are extremely rare. These tumours usually present as firm, well-defined, and elastic masses without a capsule. We present a case report with a very rare solitary neurofibroma of the palate in a four months old girl.
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Costa FWG, Carvalho FSR, Sousa CFD, Cavalcante RB, Pereira KMA. Solitary neurofibroma of the palate. Braz J Otorhinolaryngol. 2014;80:184-185.
Bharath TS, Krishna YR, Nalabolu GR, Pasupuleti S, Surapaneni S, Ganta SB. Neurofibroma of the palate. Case Rep Dent. 2014;2014:898505.
Taketomi T, Nakamura K, Teratani Y, Matsuo K, Kusukawa J. Solitary neurofibroma of the hard palate: A case report and literature review. Am J Case Rep. 2021; 22: e929674.
Allen CM, Miloro M. Gingival lesion of recent onset in a patient with neurofibromatosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;84:595-597.
Sharma P, Kamboj M, Narwal A. Palatal solitary neurofibroma simulates a salivary gland neoplam. J Oral Maxillofac Surg Med Pathol. 2020;32:76-78.
Nallanchakrava S, Mallela MK, Jeenepalli VSK, Niharika HM. A rare case report of neurofibromatosis type 1 in a 12-year-old child: A 15-month follow-up. J Oral Maxillofac Pathol. 2020;24:S106-S109.
Jangam SS, Ingole SN, Deshpande MD, Ranadive PA. Solitary intraosseous neurofibroma: Report of a unique case. Contemp Clin Dent. 2014;5: 561-563.
Ramdurg P, Puranik SR, Dantu R, Shivanand R. Solitary neurofibroma of the soft palate: A rare entity. Indian J Otolaryngol. 2019;71:38-41.
Sekhar P, Nandhini G, Kumar KR, Kumar, AR. Solitary neurofibroma of the palate mimicking mucocele: A rare case report. J Oral Maxillofac Pathol. 2019;23:23-26.
Kadarullah O. Solitary neurofibroma of the palate. In: 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021); 2022 Feb. Atlantis Press. 2022:6-10.
Alatli C, Öner B, Ünür M, Erseven, G. Solitary plexiform neurofibroma of the oral cavity: A case report. Int J Oral Max Surg. 1996;25:379-380.
Cherrick HM, Eversole LR. Benign neural sheath neoplasm of the oral cavity. Report of thirty-seven cases. Oral Surg Oral Med Oral Pathol. 1971;32:900-9.
Jain D, Chaudhary M, Patil S. Neurofibroma of the maxillary antrum: A rare case. Contemp Clin Dent. 2014;5:115-118.
Prakriti D, Junaid A, Ravikiran O, Karen B. Solitary neurofibroma of the gingival. Saudi Med J. 2014;5: 607-611.
Johann ACBR, Caldeira PC, Souto GR, Freitas JBD, Mesquita R A. Extra-osseous solitary hard palate neurofibroma. Braz J Otorhinolaryngol. 2008;74:317.
Marocchio LS, Oliveira DT, Pereira, MC, Soares CT, Fleury RN. Sporadic and multiple neurofibromas in the head and neck region: a retrospective study of 33 years. Clin Oral Invest. 2007;11:165-169.
Marx RE, Stern D. Oral and maxillofacial pathology: a rationale for diagnosis and treatment. Quintessence Publishing Co,Inc., Hanover Park,IL, USA. 2012
Awf Sh M, Bashar H, Omar M, Ameer DH. Comparative clinicopathological and immunohistochemical study of oral schwannomas and neurofibromas. J Res Med Dent Sci. 2021;9(5):27-34.
Dokania V, Rajguru A, Mayashankar V, Mukherjee I, Jaipuria B, Shere D. Palatal schwannoma: an analysis of 45 literature reports and of an illustrative case. International Archives of Otorhinolaryngology. 2019;23(03): 360-370.
Khiavi MM, Zenouz AT, Mesgarzadeh A, Sabetmehr O, Mahmoudi SM,Kouhsoltani M. Schwannoma in the midline of hard palate: a case report and review of literature. Journal of Dental research, Dental Cnics, Dental Prospects. 2014; 8(2):114.
Rai D, Shukla D, Bhola N. Case Report: Adenoid cystic carcinoma of tongue. F1000Research. 2024; 13: 276.
Saad I, Jokhadar M, Rkab M, Al Manadili A, Al-Raeei M.,Azmeh C., ... Omran W. Pedunculated oral fibroma in an 11-year-old patient: a case study. Oral Oncology Reports. 2024; 9: 100143.
Jarde SJ, Das S, Narayanswamy SA, Chatterjee A, Babu C. Mucoepidermoid carcinoma of the palate: A rare case report. Journal of Indian Society of Periodontology. 2016; 20(2):203-206.
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